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Subject: Drug Design & Medicinal Chemistry Conference - Top 5 Presentations
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If you can’t view this page, please visit: http://www.gtcbio.com/newsletter/DDMC14II-w.htm x-#

20% early bird discount ends March 8, 2014!
Drug Design & Medicinal Chemistry Conference
May 8-9, 2014 | Berlin, Germany
http://www.gtcbio.com/drugdesign

Dear Colleague,

We wanted to let you know the 20% early bird discount will be ending soon. Join colleagues from industry and academia at the Drug Design & Medicinal Chemistry Conference, May 8-9, 2014 at the Kempinski Bristol Hotel in Berlin, Germany, to learn about rising targets in protein-protein interactions, epigenetics, and in the ubiquitin proteasome system.  Hear about the latest technologies in drug discovery and using novel computational methods in medicinal chemistry.

Here are 5 presentations we don’t want you to miss:
Keynote Presentation: The Challenge to Block the Protein-Protein Interface of a Homodimer by Small Molecules
Gerhard Klebe, Professor of Pharmaceutical Chemistry, University of Marburg
Dr. Klebe’s lab showed that the tRNA-modifying enzyme Tgt, a putative target to fight Shigellosis, is only functional as a homodimer.

Local Environment of Fluorine (LEF): Screening and Drug Design
Anna Vulpetti, Senior Investigator, Novartis
This talk will discuss a novel fluorine fingerprint descriptor encoding the local environment of fluorine (LEF) for interpreting protein-fluorine interactions and for selecting the proper fluorine type for the desired interaction.

Implementation of Flow Technologies in Drug Discovery at Janssen
Jesús Alcázar, Senior Scientist, Janssen
An H-CUBE hydrogenation reactor was successfully implemented as a first approach to flow technologies. Dr. Alcázar will discuss its impact on drug discovery and the collaborations with external partners to achieve this success.

Data-Driven Medicinal Chemistry in the Era of Big-Data
Scott Lusher, Director of Applied eScience, Netherlands eScience Center
Dr. Lusher will share how data-driven medicinal chemistry approaches have the potential to improve decision-making in drug discovery projects.

Using Bioactivity Databases and Computer Algorithms for Target Deconvolution and Compound Design
Andreas Bender, Lecturer of Molecular Informatics and Drug Design, University of Cambridge
Cheminformatics algorithms trained on large chemogenomics databases can be employed to support target deconvolution in high-content screening as well as organism-based screens using Xenopus laevis as well as phenotypic data obtained from rat models.

Register before March 8, 2014 and save 20% off the registration price or use the discount code rcdvb to register three colleagues for the price of two.

The Drug Design & Medicinal Chemistry is part of the Europe Drug Discovery Summit which includes two other conferences:
Tissue Models & Drug Screening              (May 6-7, 2014)
Protein Kinases in Drug Discovery           l(May 8-9, 2014)

Sign up for a summit pass for access to all three tracks!

DISTINGUISHED SPEAKERS

Gerhard Klebe, Professor, Institute of Pharmaceutical Chemistry, University of Marburg – KEYNOTE

Jesús Alcázar, Senior Scientist, Janssen

Andreas Bender, Lecturer for Molecular Informatics and Drug Design, University of Cambridge

Jascha Blobel, Product Manager, Intelligent Pharma

Frank Boeckler, Professor, Medicinal Chemistry & Drug Design, Eberhard Karls Universität Tübingen

Helena Danielson, Professor of Biochemistry, Uppsala University

Alexander Dömling, Professor, Department of Drug Design, University of Groningen

Gerhard Ecker, Professor, Department of Medicinal Chemistry, University of Vienna

Darren Fayne, Senior Research Fellow, Trinity College Dublin

Thomas Franch, Chief Scientific Officer, Nuevolution A/S

Antimo Gioiello, Assistant Professor, Department of Pharmaceutical Sciences, University of Perugia

Nils Jakob Vest Hansen, CEO, Vipergen ApS

Katherine Jones, Associate Scientist, GlaxoSmithKline

Stefan Knapp, Professor, University of Oxford

Daniel Kuhn, Computational Chemist, Merck KG

Stig Linder, Professor of Experimental Oncology, Vice Chairman of the Department of Oncology and Pathology, Karolinska Institute

Scott Lusher, Director, Applied eScience, Netherlands eScience Center

Éric Marsault, Professor, Department of Pharmacology, Université de Sherbrooke

Ben Munoz, Vice President, Head of Medicinal Chemistry, Proteostasis Therapeutics

Christian Ottmann, Associate Professor, Biomedical Engineering, Technische Universiteit Eindhoven

Paula Petrone, Scientist, Roche

Paul Polakis, Director, Staff Scientist, Discovery Oncology, Genentech

Matthieu Schapira, Associate Professor, University of Toronto

Gisbert Schneider, Professor, Institute of Pharmaceutical Sciences, ETH Zürich

Olivier Sperandio, Drug Designer, Protein-Protein Interactions, INSERM France

Anna Vulpetti, Senior Investigator, Novartis

Steffen Weinbrenner, Head Drug Discovery, Polyphor Ltd.

Ingrid Wertz, Scientist and Project Team Leader, Department of Early Discovery Biochemistry, Genentech

View the speakers webpage for the most updated list of speakers.

CALL FOR PAPERS
To be considered for an oral presentation, please submit an abstract by April 8, 2013. Selected presentations will be based on quality of abstract and availability.
SPONSORSHIP & EXHIBITOR OPPORTUNITIES

GTC offers comprehensive sponsorship packages for all our meetings, including presentation opportunities, exhibit and booth space, as well as the event delegate list. All our packages can be customized to meet your company’s budget. For more information, please contact
Amber Kempf at 626-256-6405 x110 or [email protected]

UPCOMING CONFERENCES

4th International Conference on Tumor Progression and Therapeutic Resistance | March 9-11, 2014 | Boston, MA

Biomarker Summit 2014 | March 19-21, 2014 | San Diego, CA
7th Oncology Biomarkers
3rd Neurological Biomarkers
3rd Inflammatory & Immunological Biomarkers

6th Ocular Diseases & Drug Discovery | March 20-21, 2014 | San Diego, CA

Diabetes Summit 2014 | April 23-25, 2014 | Cambridge, MA
10% discount by March 23, 2014
7th Diabetes Drug Discovery & Development
4th Diabetes Partnering and Deal-Making

Stem Cell Summit 2014 | April 23-25, 2014 | Cambridge, MA
10% discount by March 23, 2014
Stem Cell Research & Regenerative Medicine
Stem Cell Commercialization & Partnering

Europe Drug Discovery Summit | May 6-9, 2014 | Berlin, Germany
20% discount by March 6, 2014
Tissue Models & Drug Screening              (May 6-7, 2014)
20% discount by March 8, 2014
Drug Design & Medicinal Chemistry          (May 8-9, 2014)
Protein Kinases in Drug Discovery            (May 8-9, 2014)

Drug Discovery Summit | May 22-23, 2014 | Cambridge, MA
20% discount by March 22, 2014
GPCR Structure, Function and Drug Discovery
Metabolomics: Advances & Applications in Human Diseases
Single Cell Analysis
Bioanalytical Sensors

Nucleic Acid Summit 2014 | June 19-20, 2014 | San Diego, CA
20% discount by April 19, 2014
4th Next Generation Sequencing
Bioinformatics & Pharmacogenomics: Managing and Analyzing Big Data
Non-Coding RNAs and RNAi Research & Therapeutics
Nucleic Acid Research and Discovery

Novel Cancer Therapeutics Summit 2014 | July 7-8, 2014 | Boston, MA
20% discount by May 7, 2014
5th Cancer Targets & Therapeutics
3rd Oncology Partnering & Deal-Making

Infectious Diseases World Summit 2014 | July 9-11, 2014 | Boston, MA
20% discount by May 9, 2014
12th Vaccines Research & Development: All Things Considered
11th Anti-Infectives Partnering & Deal-Making
3rd Influenza Research & Development

This advertisement is sent to x from GTC, 635 W. Foothill Blvd, Monrovia, CA 91016. If you prefer not to receive further messages from this sender, please forward this email to [email protected] or use the following link to unsubscribe http://gtcbio.com/unsubscribe.php?emailid=x